Will not flush drugs down the bathroom or pour them right into a drain unless instructed to do so. Effectively discard this item when it really is expired or no longer essential. Consult your pharmacist or community squander disposal firm.

Use an accurate measuring system to evaluate your dose of promethazine/codeine. A family spoon isn't an precise measuring product and could trigger you to get the wrong dose. Ask your pharmacist to advise an acceptable measuring unit.

Avoid the use of Promethazine HCl and Codeine Phosphate Oral Remedy in adolescents twelve to 18 years of age who have other risk components which could improve their sensitivity into the respiratory depressant outcomes of codeine.

The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people fewer than 6 a long time of age, due to the fact The mixture might induce lethal respiratory melancholy In this particular age population.

The urge to cough occurs within your brain, especially the brainstem. Opioids like codeine block this urge by Doing work onmu and kappa opioid receptorsin the brainstem.

2) Area the combination inside a sealable bag, empty can, or other container to forestall the drug from leaking or breaking out of a garbage bag, or to get rid of in accordance with community point out recommendations and/or rules.

與其它鴉片類藥物一樣，可待因的其中一個潛在的嚴重不良反應是壓抑呼吸，通常與服用過量有關，可引致死亡。

Will not consider any benzodiazepines or medicines that might cause drowsiness or sleepiness throughout cure with Promethazine Hydrochloride and Codeine Phosphate Oral Solution. website Question your Health care service provider for a list of these medicines if you are not confident.

This item may possibly result in really serious mental/mood modifications and really really serious (hardly ever deadly) respiratory difficulties. This merchandise may possibly contain codeine or dihydrocodeine. Codeine and dihydrocodeine are changed into strong opioid medication (morphine or dihydromorphine) in Your entire body.

Breathing difficulties (respiratory despair)that can lead to death and opioid withdrawal can take place if more info you start getting or halt getting other medicines whilst having Promethazine Hydrochloride and Codeine Phosphate Oral Answer, like:

Stay clear of the use of Promethazine HCl and Codeine check here Phosphate Oral Resolution in adolescents twelve to 18 many years of age who produce other hazard things that read more will increase their sensitivity into the respiratory depressant outcomes of codeine Unless of course the benefits outweigh the check here challenges.

Promethazine administered to the Expecting woman within two weeks of shipping and delivery could inhibit platelet aggregation while in the new child.

Codeine resembles morphine both equally structurally and pharmacologically, but its steps within the doses of codeine utilised therapeutically are milder, with much less sedation, respiratory despair and gastrointestinal, urinary, and pupillary outcomes. Codeine makes an increase in biliary tract stress, but lower than morphine or meperidine. Codeine is much less constipating than morphine.

Postmarketing circumstances of respiratory melancholy, which include fatalities, have been noted with use of promethazine hydrochloride in pediatric individuals below two yrs of age. A variety of pounds-centered doses of promethazine hydrochloride have resulted in respiratory despair in these individuals.